| Pair Name | Juglone, Temozolomide | ||
| Phytochemical Name | Juglone (PubChem CID: 3806 ) | ||
| Anticancer drug Name | Temozolomide (PubChem CID: 5394 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Juglone, Temozolomide | |||
| Disease Info | [ICD-11: 2A00] | Glioblastoma multiforme | Investigative | |
| Biological Phenomena | Induction-->Blockade of cell cycle in G0/G1 phase | |||
| Gene Regulation | Up-regulation | Expression | OGG1 | hsa4968 |
| In Vitro Model | T98G | Glioblastoma | Homo sapiens (Human) | CVCL_0556 |
| U-138MG | Astrocytoma | Homo sapiens (Human) | CVCL_0020 | |
| U-118MG | Astrocytoma | Homo sapiens (Human) | CVCL_0633 | |
| Result | Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line | |||
| No. | Title | Href |
|---|---|---|
| 1 | Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line. Int J Mol Sci. 2023 Apr 10;24(8):6998. doi: 10.3390/ijms24086998. | Click |
